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KMID : 0360220080490010125
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Journal of the Korean Ophthalmological Society
2008 Volume.49 No. 1 p.125 ~ p.134
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Intra-individual, Inter-ocular Comparison In Normal Tension Glaucoma with Unilateral Field Loss
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Lee Dong-Hoon
Kee Chang-won
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Abstract
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Purpose : To investigate whether there are differences in ocular risk factors reportedly associated with the
development of normal tension glaucoma (NTG) between glaucomatous eyes and normal visual field (VF)
eyes of monocular NTG patients.
Methods : Thirty-six patients who had NTG in one eye and normal RNFL and VF in the fellow eye were
included in this hospital-based cross-sectional retrospective survey. We analyzed the difference between
glaucomatous eyes and normal VF eyes according to an intra-individual, inter-ocular comparison of ocular
parameters, including intraocular pressures (IOP), central corneal thickness (CCT), optic disc size, myopia,
optic disc hemorrhage, and zone β of peripapillary atrophy. Measurements of optic disc size and area and the
angular and radial extent of zone β were obtained using a Heidelberg Retina Tomograph. We also evaluated
the correlation of each parameter with mean deviation (MD) and pattern standard deviation (PSD).
Results : There were no inter-ocular differences of IOP, CCT, optic disc size, or myopia (n=36). Optic disc
hemorrhage was found in only three glaucomatous eyes. The area of zone β was greater in glaucomatous eyes
than in normal VF eyes (p=0.003). No parameters were correlated with MD or PSD.
Conclusion : Except for optic disc hemorrhage and zone β area, all other parameters showed no inter-ocular
differences. The asymmetry of disc hemorrhage and zone β area in monocular NTG patients implies that optic
disc ischemia might play a role in the pathogenesis of NTG.
J Korean Ophthalmol Soc 49(1):125-134, 2008
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KEYWORD
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Ischemia, Normal tension glaucoma, Optic disc hemorrhage, Zone β
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